The high-level capabilities of TARGETgene are demonstrated through two examples. The two examples are illustrative of the capabilities and use of TARGETgene in identifying potential therapeutic targets from thousands of differentially expressed genes (Example 1) and driver genes (Example 2) in cancer. The complete details for the two examples, as well as background information on the constructed gene network used by TARGETgene are provided in the Supplemental Material below. Two PowerPoint files that illustrate the usage of TARGETgene in the two examples are also provided below.

Supplemental Material (PDF)
Examples (PDF)

Latest Posts About TARGETgene

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    The vast array of in silico resources currently available in the life sciences research offers the possibility of aiding the drug discovery process. Core Project 1 of the BMSR has developed TARGETgene to exploit these resources and to allow the identification of potential therapeutic targets and drugs in cancer using genetic network-based approaches. TARGETgene is…Continue Reading Release of TARGETgene