Modeling the Metabolic Syndrome

An extensive overview of the efforts that have been made to better understand the pathophysiology of metabolic syndrome using computational modeling was published in the ...Read more

Core Research #1

Pharmacokinetic / Pharmacodynamic Modeling & Systems Analysis
David Z. D’Argenio, Ph.D.

Core Research #2

Core Research #3

Models of Multi-Factor Disorders in Cardiorespiratory Control
Michael C.K. Khoo, Ph.D.

Core Research #4

Multi-Scale Modeling of Hippocampal Dynamics and Neural Prostheses
Theodore W. Berger, Ph.D.


Four Core Research projects develop advanced biomedical systems modeling and simulation methodologies and tools focusing on the challenging cases of nonlinear, nonstationary, sparse data and feedback systems.

Collaborative Research projects serve as challenging test beds for the Resource’s methodologies and expertise, while addressing translational and clinical problems in: cardiovascular/respiratory & metabolic diseases; neurovascular & neurodegenerative diseases; neurostimulation & functional neurosurgery; and oncology & infectious diseases.

The BMSR’s Service activities include the distribution and user support of our software tools ADAPT, EONS, LYSIS, PNEUMA & TARGETgene.

The Resource’s Training and Dissemination activities include software and methodology short courses, workshops and sponsorship of meetings and symposia.

The BMSR is support through grant P41-EB001978 from the National Institute of Biomedical Imaging and Bioengineering of the NIH and has been continuously funded as an NIH Research Resource since 1985.