Core & Collaborative Research

Journal publications presenting research results from individual Core and associated Collaborative projects can be accessed via the links below to each Core project.

Core Project # 1 – David Z. D’Argenio
Pharmacokinetic/Pharmacodynamic Systems Modeling & Analysis

Core Project #2 – Vasilis Z. Marmarelis
Nonlinear Modeling of Complex Biomedical Systems

Core Project #3 – Michael C.K. Khoo
Modeling of Autonomic, Metabolic and Vascular Control Interactions

Core Project #4 – Theodore W. Berger
Nonlinear Modeling of the Hippocampus

Editorials and White Papers with BMSR Core Project Leaders

Frangi, A.F., Coatrieux, J.L., Peng, G.C., D’Argenio, .D.Z., Marmarelis, V.Z. and A. Michailova. Editorial: Special issue on multiscale modeling and analysis in computational biology and medicine-Part-1. IEEE Transaction of Biomedical Engineering58(10):2936-2942, 2011.  [PDF]

Coatrieux, J.L.,  Frangi, A.F., Peng, G.C., D’Argenio, .D.Z., Marmarelis, V.Z. and A. Michailova. Editorial: TBME letters special issue on multiscale modeling and analysis in computational biology and medicine-Parts-2. IEEE Transaction of Biomedical Engineering58(12):3433-3439, 2011. [PDF]

Sorger,P.K., Allerheiligen, S.R.B, Abernethy, D.R., Altman, R.B., Brouwer, K.L.R., Califano, A., D’Argenio, D.Z., Iyengar, R., Jusko, W.J., Lalonde, R., Lauffenburger, D.A., Shoichet, B., Stevens, J.L., Subramaniam, S., Van der Graaf, P,  and Vicini, P. Quantitative and systems pharmacology in the post-genomic era: New approaches to discovering drugs and understanding therapeutic mechanisms. An NIH White Paper by the QSP Workshop Group, pp 1-48, 2011. [PDF]

Pfister, M. and D.Z. D’Argenio. The emerging scientific discipline of pharmacometrics. Journal of Clinical Pharmacology 50(9):6S, 2010. [PDF]

D’Argenio, D.Z. and D.E. Mager. Bridging pharmacology and pathophysiology via systems modeling. Journal of Clinical Pharmacology 50:56S-57S, 2010. [PDF]

Monographs and Research Volumes from Past Workshops

2005
Towards Replacement Parts for the Brain – Implantable Biomimetic Electronics as Neural Protheses
Theodore W. Berger, Ph.D., Dennis L. Glanzman & Ph.D.Vasilis Z. Marmarelis, Ph.D.

2004
Nonlinear Dynamic Modeling of Physiological Systems
Vasilis Z. Marmarelis, Ph.D.

Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis – Volume III
David Z. D’Argenio, Ph.D.

2000
Physiological Control Systems Analysis, Simulation, and Estimation
Michael C.K. Khoo, Ph.D.

1996
Bioengineering Approaches to Pulmonary Physiology and Medicine
Michael C.K. Khoo, Ph.D.

1995
Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis – Volume II
David Z. D’Argenio, Ph.D.

1994
Advanced Methods of Physiological System Modeling – Volume III
Vasilis Z. Marmarelis, Ph.D.

1991
Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis – Volume I
David Z. D’Argenio, Ph.D.

1989
Advanced Methods of Physiological System Modeling – Volume II
Vasilis Z. Marmarelis, Ph.D.

Modeling and Parameter Estimation in Respiratory Control
Michael C.K. Khoo, Ph.D.

1987
Advanced Methods of Physiological System Modeling – Volume I
Vasilis Z.Marmarelis, Ph.D.