EONS

(Elementary Objects of the Nervous System)

System Requirements

EONS V1.2 is a Windows program but can be also successfully installed and run on Mac and Linux. Please go to the HELP section for more details.

Hardware Requirements

• Display
  • Minimum: 1024×768, 16 bit color, 17” monitor
  • Recommended: 1280×1024 or higher, 32 bit color, 19” monitor
• Suggested Memory
  • Minimum: At least 512MB RAM
  • Recommended: 1GB RAM
• Internet Connection
  • Minimum: Dialup
  • Recommended: T1/T3/Cable Modem/DSL

Our research focus consists in modeling hippocampal synaptic nonlinear dynamics and understanding their challenging complexity. Such modeling consists in understanding the role of the elements that comprise a synapse and participate in the transmission of information from the presynaptic terminal to post-synaptic density and more generally from a neuron to another. This also involves understanding the different interactions that exist between these elements and how geometry affects synaptic response.

Our research is done through a modeling platform called EONS (Elementary Objects of the Nervous System). This platform consists of a graphical interface in which elements that comprise a single glutamatergic synapse (both pre- and post-synaptically), their behavior as well as the underlying synaptic geometry can be modified. For example, EONS offers the ability to study the effect of voltage-gated calcium channels density and distribution, the number and location of receptors and more.

EONS v1.2

EONS v1.2 is the perfect tool to study the basic interactions between synaptic elements in a friendly manner. There are no complicated equations to write: all the models are predefined! This version is a great tool for first time users and students interested in learning about synapses, as well as for studying geometry and distribution hypotheses in a 2D rectangular geometry.

Notes for Mac and Linux users:

Do you have a Mac or Linux? Not a problem! It is possible to easily install EONS as well (this was tested successfully on OS 10.5+ and Ubuntu) using applications that create in a straight forward manner a virtual Windows environment. Please see the HELP section for further details.

Other projects

Contour Generator (August 4, 2004)
In this application, the user can delineate the contours of a structure using a jpeg/gif image. The generated contours file becomes an input to the Mesh2D software to generate a 2D mesh.

Differential Equation Generator (January 24, 2006)
In this application, the user can interactively design kinetic equations and generate the corresponding equations that can be directly plugged into EONS.