Category: EONS

Note: Improved user interface: addition of zoom-in/out and pause options during simulation. Added mechanism: nicotinic acetylcholine receptor…Continue Reading EONS V1.0

Note: With long simulations, the simulations recorded too many points which resulted in very important memory usage. The user can now select how many points will be stored at the end of the simulation, resulting in a significantly lower amount of memory used….Continue Reading EONS V1.0

Note: With long simulations, the graphs contained too many points which induced very slow update of the display when the user was switching graphs or scrolling up and down. A new class checks for the significance of the points to be displayed and hence only displays the significant ones, resulting in much faster drawing. Updated…Continue Reading EONS V1.0

Note: The animation flickering problem encountered on some machines is fixed; Increase in simulation speed….Continue Reading EONS V1.0

Note: This version contains new postsynaptic models: slow and medium potassium channels and new Na/Ca exchanger. This version includes all features previously available….Continue Reading EONS V1.0

Note: This version was completely remodeled. It contains new models for calcium pumps (N, L and T types), new neurotranmitter release and new receptors kinetics. the interface is completely rewritten. This version includes all features previously available….Continue Reading EONS V1.0

Note: This version of the model includes all features previously available. Calcium pumps and localized buffers can be eliminated. The neurotransmitter release approximation using a fourth power rule has been modified; a bug in the calcium channel dynamics has also been fixed….Continue Reading EONS Beta7 Version

Note: This version of the model includes all features previously available. The synaptic cleft has now variable width. It can vary from 6 to 40 nm (in 2nm increments)….Continue Reading EONS Beta6 Version

Note: This version of the model includes all features previously available. The login on the applet is disabled. Labels are added for a more user-friendly interface. The online help is updated….Continue Reading EONS Beta5 Version

Note: This version of the model includes all features previously available. An animation illustrates the evolution of calcium concentration in the presynaptic terminal as well as the evolution of neurotransmitter concentration in the cleft during the simulation….Continue Reading EONS Beta4 Version