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System Requirements for ADAPT

ADAPT only runs under the Microsoft Windows Operating System (XP/Server 2003/Vista). Prior to installing ADAPT, you will need to install one of the supported compilers. At present this includes the Intel Fortran Compiler 9.1-11.0 and the Compaq Fortran Compiler v6.6. The Intel Fortran Compiler license will allow you to download two versions of the compiler: one that is integrated with the Microsoft Visual Studio (MVS) and one that requires MVS to be installed separately. The former is the most straightforward, if you don’t have MVS on your machine

Release of ADAPT 5

ADAPT 5 represents a major new version of ADAPT with expanded capabilities and other enhancements, including Parametric population PK/PD modeling using maximum likelihood estimation via the EM algorithm (MLEM module) as introduced by Schumitzky (1995) and Walker (1996), with enabling computational enhancements and extensions by Bauer and Guzy (2004). In addition, ADAPT 5 includes Iterated two-stage (ITS) analysis as proposed by Prevost (1977) and Steimer, Mallet and colleagues (1984), as well as convenient standard two-stage (STS) and naive pooled data (NPD) modeling, each with WLS, ML and MAP estimator.

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