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  2. Abraham, A., T. Maurer, A. Kalgutkar, X. Gao, M. Li, D. Healy, and D. Mager. Pharmacodynamic model of parathyroid hormone modulation by a negative allosteric modulator of the calcium-sensing receptor. The American Association of Pharmaceutical Scientists Journal 13(2):265-273, 2011.
  3. Baek, I.H., W. Kang, H.Y. Yun, S.S. Lee, and K.I. Kwon. Modelling the atypical absorption of menatetrenone and the metabolism to its epoxide: effect of VKORC1 polymorphism. Journal of Clinical Pharmacy and Therapeutics 36(3):390-398, 2011.
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  9. Brown, A.N., J.B. Bulitta, J.J. McSharry, Q. Weng, J.R. Adams, R. Kulawy, and G.L. Drusano. Effect of half-life on the pharmacodynamic index of zanamivir against influenza virus delineated by a mathematical model Antimicrobial Agents and Chemotherapy 55(4):1747-1753, 2011.
  10. Brown, A.N., J.J. Mcsharry, Q. Weng, J.R. Adams, R. Kulawy, and G.L. Drusano. Zanamivir, at 600 milligrams twice daily, inhibits oseltamivir-resistant 2009 pandemic H1N1 inluenza vrus in an in vitro hollow-fiber infection model system. Antimicrobial Agents and Chemotherapy 55(4):1740-1746, 2011.
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  18. Chan, P., P. Jacqmin, M. Lavielle, L. McFadyen,and B. Weatherley. The use of the SAEM algorithm in MONOLIX software for estimation of population pharmacokinetic-pharmacodynamic-viral dynamics parameters of maraviroc in asymptomatic HIV subjects Journal of Pharmacokinetics and Pharmacodynamics 38(1):41-61, 2011.
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  22. Drusano, G.L., W. Liu, R. Kulawy, and A. Louie. Impact of granulocytes on the antimicrobial effect of tedizolid in a mouse thigh infection model. Antimicrobial Agents and Chemotherapy 55(11):5300-5305, 2011.
  23. Drusano, G.L., T.P. Lodise, D. Melnick, W. Liu, A. Oliver, A. Mena, and A. Louie. Meropenem penetration into epithelial lining fluid in mice and men and delineation of exposure targets. Antimicrobial Agents and Chemotherapy 55(7):3406-3412, 2011.
  24. Drusano, G.L. and A. Louie. Optimization of aminoglycoside therapy. Antimicrobial Agents and Chemotherapy 55(6):2528-2531, 2011.
  25. Drusano, G.L. Effect of administration of moxifloxacin plus rfampin against mycobacterium tuberculosis for 7 of 7 days versus 5 of 7 days in an in vitro pharmacodynamic system. mBio 2(4):2011.
  26. Elmeliegy, M.A., A.M. Carcaboso, M. Tagen, F. Bai, C.F. Stewart. Role of ATP-binding cassette and solute carrier transporters in erlotinib CNS penetration and intracellular accumulation. Clinical Cancer Research 17(1):89-99, 2011.
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  31. Gao, W., and W.J. Jusko. Pharmacokinetic and pharmacodynamic modeling of exendin-4 in type 2 diabetic goto-kakizaki rats. Journal of Pharmacology and Experimental Therapeutics 336(3):881-890, 2011.
  32. Garonzik, S.M., J. Li, V. Thamlikitkul, D.L. Paterson, S. Shoham,…and R.L. Nation. Population pharmacokinetics of colistin methanesulfonate and formed colistin in critically ill patients from a multicenter study provide dosing suggestions for various categories of patients. Antimicrobial Agents and Chemotherapy 55(7):3284-3294, 2011.
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  34. Hall, R.G., M.A. Swancutt, and T. Gumbo. Fractal geometry and the pharmacometrics of micafungin in overweight, obese, and extremely obese people. Antimicrobial Agents and Chemotherapy 55(11):5107-5112, 2011.
  35. Hao, K., P. Gong, S.-Q. Sun, H.-P. Hao, G.-J. Wang, Y. Dai, and H.-Y. Li. Mechanism-based pharmacokinetic-pharmacodynamic modeling of the estrogen-like effect of ginsenoside Rb1 on neural 5-HT in ovariectomized mice. European Journal of Pharmaceutical Sciences 44(1-2):117-126, 2011.
  36. Jasinski, P., P. Zwolak, R.I. Vogel, V. Bodempudi, K. Terai, J. Galvez, and A. Dudek. MT103 inhibits tumor growth with minimal toxicity in murine model of lung carcinoma via induction of apoptosis. Investigational New Drugs 29(5):846-852, 2011.
  37. Jasinski, P., P. Zwolak, K. Terai, R. I. Vogel, D. Borja-Cacho, and A.Z. Dudek. MT477 acts in tumor cells as an AURKA inhibitor and strongly induces NRF-2 signaling. Anticancer Research 31(4):1181-1187, 2011.
  38. Jeena, P.M., W.R. Bishai, J.G. Pasipanodya, and T. Gumbo. In silico children and the glass mouse model: clinical trial simulations to identify and individualize optimal isoniazid doses in children with tuberculosis. Antimicrobial Agents and Chemotherapy 55(2):539-545, 2011.
  39. Kagan, L., P. Gershkovich, K. Wasan, D. Mager. Physiologically based pharmacokinetic model of amphotericin B disposition in rats following administration of deoxycholate formulation (Fungizone®): pooled analysis of published data. The American Association of Pharmaceutical Scientists Journal 13(2):255-264, 2011.
  40. Kang, W. Myocardial pharmacokinetics of ebastine, a substrate for cytochrome P450 2J, in rat isolated heart. British Journal of Pharmacology 163(8):1733-1739, 2011.
  41. Kebriaei, P., T. Madden, R. Kazerooni, X. Wang, P.F. Thall, C. Ledesma, and B.S. Andersson. Intravenous busulfan plus melphalan is a highly effective, well-tolerated preparative regimen for autologous stem cell transplantation in patients with advanced lymphoid malignancies. Biology of Blood and Marrow Transplantation 17(3):412-420, 2011.
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  45. Liu, D., H.-K. Lon, D. DuBois, R. Almon, W. Jusko. Population pharmacokinetic-pharmacodynamic-disease progression model for effects of anakinra in lewis rats with collagen-induced arthritis. Journal of Pharmacokinetics and Pharmacodynamics 38(6):769-786, 2011.
  46. Lodise, T.P., F. Sorgel, D. Melnick, B. Mason, M. Kinzig, and G.L. Drusano. Penetration of meropenem into epithelial lining fluid of patients with ventilator-associated pneumonia. Antimicrobial Agents and Chemotherapy 55(4):1606-1610, 2011.
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  48. Louie, A., H.S. Heine, B. Vanscoy, A. Eichas, K. Files, S. Fikes, and G.L. Drusano. Use of an in vitro pharmacodynamic model to derive a moxifloxacin regimen that optimizes kill of yersinia pestis and prevents emergence of resistance. Antimicrobial Agents and Chemotherapy 55(2):822-830, 2011.
  49. Louie, A., W. Liu, R. Kulawy, and G.L. Drusano. In vivo pharmacodynamics of torezolid phosphate (TR-701), a new oxazolidinone antibiotic, against methicillin-susceptible and methicillin-resistant staphylococcus aureus in a mouse thigh infection model. Antimicrobial Agents and Chemotherapy 55(7):1606-1610, 2011.
  50. Marathe, D.D., A. Marathe, and D.E. Mager. Integrated model for denosumab and ibandronate pharmacodynamics in postmenopausal women. Biopharmaceutics and Drug Disposition 32(8):471-481, 2011.
  51. Markakis, M.G., G.D. Mitsis, G.P. Papavassilopoulos, P.A. Ioannou and V.Z. Marmarelis. A switching control strategy for the attenuation of blood glucose disturbances. Optimal Control Applications and Methods 32(2): 185-195, 2011.
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  55. Nemeth, K.M., S. Federico, A.M. Carcaboso, Y. Shen, P. Schaiquevich, J. Zhang, . . .and M.A. Dyer. Subconjunctival carboplatin and systemic topotecan treatment in preclinical models of retinoblastoma. Cancer 117(2):421-434, 2011.
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  57. Pai, M.P., and L.P. Thomas. Oseltamivir and oseltamivir carboxylate pharmacokinetics in obese adults: dose modification for weight is not necessary. Antimicrobial Agents and Chemotherapy 55(12):5640-5645, 2011.
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  59. Pasipanodya, J. and T. Gumbo. An oracle: antituberculosis pharmacokinetics-pharmacodynamics, clinical correlation, and clinical trial simulations to predict the future. Antimicrobial Agents and Chemotherapy 55(1):24-34, 2011.
  60. Patel, N., K. Cardone, D.W. Grabe, S. Meola, C. Hoy, H. Manley, and T.P. Lodise. Use of pharmacokinetic and pharmacodynamic principles to determine optimal administration of daptomycin in patients receiving standardized thrice-weekly hemodialysis. Antimicrobial Agents and Chemotherapy 55(4):1677-1683, 2011.
  61. Patel, N., M.P. Pai, K.A. Rodvold, B. Lomaestro, G.L. Drusano, and T.P. Lodise. Vancomycin: we can’t get there from here. Clinical Infectious Diseases 52(8):969-974, 2011.
  62. Pietanza, M.C., S.M. Gadgeel, A. Dowlati, T.J. Lynch, R. Salgia, K.M. Rowland, Jr., . . .and N.A. Rizvi. Phase II study of the multitargeted tyrosine kinase inhibitor XL647 in patients with non-small-cell lung cancer. Journal of Thoracic Oncology 7(5): 856-865, 2011.
  63. Prémaud, A., L.T. Weber, B. Tönshoff, V.W. Armstrong, M. Oellerich, S. Urien, A. Rousseau. Population pharmacokinetics of mycophenolic acid in pediatric renal transplant patients using parametric and nonparametric approaches. Pharmacological Research 63(3):216-224, 2011.
  64. Prokocimer, P., P. Bien, J. Surber, P. Mehra, C. DeAnda, J.B. Bulitta, and G.R. Corey. Phase 2, randomized, double-blind, dose-ranging study evaluating the safety, tolerability, population pharmacokinetics, and efficacy of oral torezolid phosphate in patients with complicated skin and skin structure infections. Antimicrobial Agents and Chemotherapy 55(2):583-592, 2011.
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  70. Shah, D., and A. Betts. Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human. Journal of Pharmacokinetics and Pharmacodynamics 39(1):67-86, 2011.
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  74. Song, J.S., H.J. Rho, J.S. Park, M.S. Kim, B.H. Lee, J.-W. Seo, and M.A. Bae. Preclinical pharmacokinetics of PDE-310, a novel PDE4 inhibitor. Drug Metabolism and Pharmacokinetics 26(2):192-200, 2011.
  75. Soto, E., A. Staab, C. Doege, M. Freiwald, G. Munzert, and I. Trocóniz. Comparison of different semi-mechanistic models for chemotherapy-related neutropenia: application to BI 2536 a Plk-1 inhibitor. Cancer Chemotherapy and Pharmacology 68(6):1517-1527, 2011.
  76. Srivastava, S., J. Pasipanodya, C. Meek, R. Leff, and T. Gumbo. Multidrug-resistant tuberculosis not due to noncompliance but to between-patient pharmacokinetic variability. Journal of Infectious Diseases 204(12):1951-1959, 2011.
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