Core Research
Pharmacokinetic / Pharmacodynamic Modeling & Systems Analysis
David Z. D’Argenio, Ph.D.
Co-Director
Biomedical Systems Modeling for Improved Clinical Diagnosis & Treatment
Vasilis Z. Marmarelis, Ph.D.
Co-Director
Models of Multi-Factor Disorders in Cardiorespiratory Control
Michael C.K. Khoo, Ph.D.
Co-Investigator
Multi-Scale Modeling of Hippocampal Dynamics and Neural Prostheses
Theodore W. Berger, Ph.D.
Co-Investigator
The BMSR is dedicated to the advancement of the state-of-the-art in biomedical systems modeling and simulation through Core and Collaborative Research projects, as well as the dissemination of this knowledge and related software through Service, Training and Dissemination activities.
Overview
Four Core Research projects develop advanced biomedical systems modeling and simulation methodologies and tools focusing on the challenging cases of nonlinear, nonstationary, sparse data and feedback systems.
Collaborative Research projects serve as challenging test beds for the Resource’s methodologies and expertise, while addressing translational and clinical problems in: cardiovascular/respiratory & metabolic diseases; neurovascular & neurodegenerative diseases; neurostimulation & functional neurosurgery; and oncology & infectious diseases.
The BMSR’s Service activities include the distribution and user support of our software tools ADAPT, EONS, LYSIS, PNEUMA & TARGETgene.
The Resource’s Training and Dissemination activities include software and methodology short courses, workshops and sponsorship of meetings and symposia.
The BMSR has been supported through NIH grant P41-EB001978 from the National Institute of Biomedical Imaging and Bioengineering and P41-RR0161 from the National Center for Research Resources.