All posts from EONS
Note: Improved user interface: addition of zoom-in/out and pause options during simulation. Added mechanism: nicotinic acetylcholine receptor
Note: With long simulations, the simulations recorded too many points which resulted in very important memory usage. The user can now select how many points will be stored at the end of the simulation, resulting in a significantly lower amount of memory used.
Note: With long simulations, the graphs contained too many points which induced very slow update of the display when the user was switching graphs or scrolling up and down. A new class checks for the significance of the points to be displayed and hence only displays the significant ones, resulting in much faster drawing. Updated to the latest versions of JDK (1.5.0_11), JFreechart (1.0.3) and JCommon (1.0.8)
Note: The animation flickering problem encountered on some machines is fixed; Increase in simulation speed.
Note: This version contains new postsynaptic models: slow and medium potassium channels and new Na/Ca exchanger. This version includes all features previously available.
Note: This version was completely remodeled. It contains new models for calcium pumps (N, L and T types), new neurotranmitter release and new receptors kinetics. the interface is completely rewritten. This version includes all features previously available.
Note: This version of the model includes all features previously available. Calcium pumps and localized buffers can be eliminated. The neurotransmitter release approximation using a fourth power rule has been modified; a bug in the calcium channel dynamics has also been fixed.
Note: This version of the model includes all features previously available. The synaptic cleft has now variable width. It can vary from 6 to 40 nm (in 2nm increments).
Note: This version of the model includes all features previously available. The login on the applet is disabled. Labels are added for a more user-friendly interface. The online help is updated.
Note: This version of the model includes all features previously available. An animation illustrates the evolution of calcium concentration in the presynaptic terminal as well as the evolution of neurotransmitter concentration in the cleft during the simulation.