ADAPT
5 represents a major new
version of ADAPT and includes the addition of population
modeling
capabilities. In accomplishing these additions and enhancements we have
worked
to
maintain the programs generality, flexibility and computational
robustness.
We would like to thank
some current and former graduate students and postdoctoral fellows who have
contributed to the testing and evaluation of ADAPT 5: Phyllis Chan, Joy
Hsu,
Ritesh Jain, Dongwoo Kang, Brittany Kay, Tong Lu, Gabriela
Mallen-Ornelas, Kyung-Soo Park, Min-Hyung Park, Nathalie Poupin, Linh Van, Jian
Wang, Xiaoning Wang, Lu Xu, Zexun Zhou, and Rui Zhu. We also
acknowledge Ashutosh
Gandhi for programming the ADAPT 5 interface, Amy Joe for help with the
ADAPT
Library, and Andrew Bae and Christine Lee for their work on this User’s
Guide
and the BMSR web site. We gratefully express our
appreciation to BMSR
collaborators and other colleagues for their suggestions and for
providing
stimulating applications: Edward Acosta, Michael Amentea, Kyun-Seop Bae,
Robert Bauer, Stacey
Berg, Paul Berringer, Jan Beumer, Richard Brundage, Jurgen
Bulitta, George Drusano,
Murray Ducharme,
Laszlo Endrenyi, Merrill Egorin, Julie Eiseman, Courtney Fletcher, Alan
Forrest, Iztok Grabnar, Mathew Hsu, Shasha Jumbe, William Jusko, Wojciech
Krzyzanski, Jean Lavigne,
Jian-Feng Lu, Donald Mager, Daniel
Maneval, Giovanni Pacini, Carl Panetta, Mark Ratain, Mary Relling,
Keith
Rodvold, Gary Rosner, Thomas Sun, Jurgen Venitz, Davide Verotta, Paolo
Vicini,
Jon Wakefield, and Michael Weiss.
The feedback and advice we continue to receive from many users (far too
many to list here) have served as an important impetus for the
significant
enhancements included in ADAPT 5; we greatly appreciate your
contributions. As
always, please contact us with any questions, suggestions and comments
about
ADAPT, as well as corrections and suggestions for this User’s Guide.
ADAPT has been
developed by the Biomedical Simulations Resource at the University of
Southern
California, under support from the National Institute for Biomedical
Imaging
and Bioengineering (NIBIB) at the National Institutes of Health.
(P41-RR01861). We gratefully acknowledge the advice and support of Dr.
Grace
Peng, Program Director at NIBIB over the past years. Over the past 10
years the
BMSR has been the fortunate beneficiary of the
expert administrative skills of
Marcos Briano – thank you Marcos!
It is with great pleasure and immense gratitude that we dedicate this
User’s Guide to Roger W. Jelliffe and to the memory of John Rodman.
Los
Angeles
David Z. D'Argenio
July
2009
Alan Schumitzky
Xiaoning Wang
