ADAPT 5
Features
Individual Analysis Capabilities- Estimation module (ID) includes weighted least squares, maximum likelihood (ML), generalized least squares (GLS), maximum a posterior Bayesian estimation (MAP)
- Simulation module (SIM) includes capabilities for single and multisubject simulations with clinicially relevant covariates, with user defined PK/PD and covariate models
- Sample schedule design module (SAMPLE) provides the ability to calculate D- and C-optimal designs
- Parametric maximum likelihood estimation (without model linearization) via the EM algorithm (MLEM module)
- Iterative two-stage (ITS) analysis
- Convenient standard two stage (STS) and naive pooled data (NPD) modeling, each with WLS, ML and MAP estimators
Requirements
Operating System- Windows 2000/XP/Vista
- Intel Visual Fortran 10.1 or
- Intel Visual Fortran 8.0-10.0 with Microsoft Visual Studio or
- Compaq 6.6
To
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Your receipt and use of ADAPT 5 is subject to the following terms and
conditions:
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I will not distribute ADAPT 5, in whole or part, to others without the expressed permission of the Biomedical Simulations Resource (BMSR).
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I understand that neither the University of Southern California (USC) nor the BMSR make any warranties, expressed or implied, that ADAPT 5 is free of errors or is consistent with any standard of merchantability, or that it will meet my requirements for any particular application. I understand that ADAPT 5 should not be relied on for solving a problem whose incorrect solution could result in injury to a person or loss of property, and that if I do use ADAPT 5 in such a manner it is at my own risk. I understand that USC, the BMSR and the authors disclaim any and all liability for direct or consequential damages resulting from my use of ADAPT 5.
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