Advanced
Methods of
Pharmacokinetic & Pharmacodynamic Systems Analysis
Volume II (1995)
The contributions to Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis – Volume II reflect the vital synergy between modeling and experimentation that is the hallmark of pharmacokinetic and pharmacodynamic investigation. This volume includes contributions in the following areas:
- physiological and biochemical basis of pharmacokinetics
- methods and models in pharmacodynamic analysis
- novel methodologies for pharmacokinetic/dynamic modeling and estimation
- sample schedule and dose regimen design in clinical trials
Table of Contents
Modeling
of Metabolite Disposition
K.S.
Pang
H. Chang
Evaluation of Drug Interaction with Anti-HIV Nucleosides in Animal Models
M. Qian & J.M. Gallo
Modeling
Multiple Pharmacodynamic End Points
G.L.
Rosner & P. Muller
Pharmacokinetic
and Pharmacodynamic Modeling in Drug
Development
H.
Lemmens
J.W. Mandema, D. Verotta & L.B. Sheiner
Distribution Kinetics in the Body and Single Organisms: Moment Analysis
M. Weiss
Application of Neural Networks in Pharmacodynamics
P.
Veng-Pedersen
D. Verotta
EM Algorithms and Two Stage Methods in Pharmacokinetic Population Analysis
A. Schumitzky
Smoothed
Psuedo-Likelihood Estimator for Stochastic Dynamic
Systems
R.
Zhang & D.Z. D'Argenio
P.R. Hutson, K.D. Tutsch & G. Wilding
Stochastic Control of Pharmacodynamic Processes with Application of Ergotamine
K. Park & D.Z. D'Argenio
