Biomimetic Electronics as Neural Prothesis (2005)
by Theodore W. Berger, Ph.D. & Dennis L. Glanzman, Ph.D.
The continuing development of implantable neural prostheses signals a new era in bioengineering and neuroscience research. This collection of essays outlines current advances in research on the intracranial implantation of devices that can communicate with the brain in order to restore sensory, motor, or cognitive functions. The contributors explore the creation of biologically realistic mathematical models of brain function, the production of microchips that incorporate those models, and the integration of microchip and brain function through neuron-silicon interfaces. Recent developments in understanding the computational and cognitive properties of the brain and rapid advances in biomedical and computer engineering both contribute to this cutting-edge research.
The book first examines the development of sensory system prostheses -- cochlear, retinal, and visual implants -- as the best foundation for considering the extension of neural prostheses to the central brain region. The book then turns to the complexity of neural representations, offering, among other approaches to the topic, one of the few existing theoretical frameworks for modeling the hierarchical organization of neural systems. Next, it examines the challenges of designing and controlling the interface between neurons and silicon, considering the necessity for bidirectional communication and for multiyear duration of the implant. Finally, the book looks at hardware implementations and explores possible ways to achieve the complexity of neural function in hardware, including the use of VLSI and photonic technologies.
I Sensory Systems
We Made the Deaf Hear. Now What?
G.E.
Loeb
Microelectronic
Array for Stimulation of
Large Retinal Tissue Areas
D.
Scribner, M. Humayun, B. Justus, C. Merritt, R. Klein,
J.G. Howard, M. Peckerar, F. K. Perkins, E. Margalit,
K.-G. Au Eong, J. Weiland, E. de Juan, Jr., J. Finch, R. Graham,
C. Trautfield and S. Taylor
Imaging
Two-Dimensional Neural Activity
Patterns in the Cat Visual Cortex using a Multielectrode Array
D.J.
Warren, R.A. Normann and A. Koulakov
II Neural Representations
Brain Parts on Multiple Scales: Examples from the Auditory
System
E.
Covey
A
Protocol for Reading the Mind
H.
Eichenbaum
Cognitive
Processes in Replacement Brain
Parts: A Code for All Reasons
R.
Hampson, J. Simeral and S.A. Deadwyler
Mathematical
Modeling as a Basic Tool for
Neuromimetic Circuits
G.A.
Chauvet, P. Chauvet and T.W. Berger
Real-Time
Spatiotemporal Databases to
Support Human Motor Skills
S.
Ghandeharizadeh
III Neuron/Silicon Interfaces
Long-Term Functional Contact between Nerve Cell Networks and
Microelectrode Arrays
G.W.
Gross, E. Dian, E.G. Keefer, A. Gramowski and S. Stuewe
Building
Minimalistic Hybrid Neuroelectric
Devices
J.J.
Hickman
The
Biotic/Abiotic Interface: Achievements
and Foreseeable Challenges
R.D.
Brinton, W. Sousou, M. Baudry, M. Thompson and T.W.
Berger
IV Hardware Implementations
Brain-Implantable Biomimetic Electronics as a Neural
Prosthesis for
Hippocampal Memory Function
T.W.
Berger, R.D. Brinton, V.Z. Marmarelis, B.J. Sheu and
A.R.
Tanguay, Jr.
Brain
Circuit Implementation: High-Precision
Computation from Low-Precision Components
R.
Granger
Hybrid
Electronic/Photonic Multichip Modules
for Vision and Neural Prosthetic Applications
A.R.
Tanguay, Jr. and B.K. Jenkins
Reconfigurable
Processors for Neural
Prostheses
J.
Mumbru, K.V. Shenoy, G. Panotopoulos, S. Ay, X. An, F. Mok and
D. Psaltis
The
Coming Revolution: The Merging of
Computational Neural Science and Semiconductor Engineering
D.
Hammerstorm
